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Since 2020, the "rules of engagement" for our health system, the expected and relatively predictable level of ill-health in the community, have changed.1 COVID-19 has increased demand for healthcare through multiple pathways. [...]through managing those acutely unwell with COVID-19 infection, which during 2022 has been a significant source of hospitalisation over the three waves. [...]by creating a large burden of "catch up" care needed for those people whose care was delayed due to beds being occupied by those infected with COVID-19. While there is common perception that pub- lic health actions take decades to have impacts, the authors of these blogs identified a wide range of interventions that would have such as vaccination, raising alcohol taxes, lowering drink driving levels, a health-based approach to drug harms, speed limit reductions, increasing benefit levels, alterations to streets to promote cycling and walking and reformulation of processed foods.12-17 These interventions would impact on a wide range of health conditions, both physical and mental.
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INTRODUCTION: Previous novel COVID-19 pandemics, SARS and middle east respiratory syndrome observed an association of infection in pregnancy with preterm delivery, stillbirth and increased maternal mortality. COVID-19, caused by SARS-CoV-2 infection, is the largest pandemic in living memory.Rapid accrual of robust case data on women in pregnancy and their babies affected by suspected COVID-19 or confirmed SARS-CoV-2 infection will inform clinical management and preventative strategies in the current pandemic and future outbreaks. METHODS AND ANALYSIS: The pregnancy and neonatal outcomes in COVID-19 (PAN-COVID) registry are an observational study collecting focused data on outcomes of pregnant mothers who have had suspected COVID-19 in pregnancy or confirmed SARS-CoV-2 infection and their neonates via a web-portal. Among the women recruited to the PAN-COVID registry, the study will evaluate the incidence of: (1) miscarriage and pregnancy loss, (2) fetal growth restriction and stillbirth, (3) preterm delivery, (4) vertical transmission (suspected or confirmed) and early onset neonatal SARS-CoV-2 infection.Data will be centre based and collected on individual women and their babies. Verbal consent will be obtained, to reduce face-to-face contact in the pandemic while allowing identifiable data collection for linkage. Statistical analysis of the data will be carried out on a pseudonymised data set by the study statistician. Regular reports will be distributed to collaborators on the study research questions. ETHICS AND DISSEMINATION: This study has received research ethics approval in the UK. For international centres, evidence of appropriate local approval will be required to participate, prior to entry of data to the database. The reports will be published regularly. The outputs of the study will be regularly disseminated to participants and collaborators on the study website (https://pan-covid.org) and social media channels as well as dissemination to scientific meetings and journals. STUDY REGISTRATION NUMBER: ISRCTN68026880.